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— George Henry Lewes"Metaphysical ghosts cannot be killed, because they cannot be touched; but they may be dispelled by dispelling the twilight in which shadows and solidities are easily confounded. The Vital Principle is an entity of this ghostly kind; and although the daylight has dissipated it, and positive Biology is no longer vexed with its visitations, it nevertheless reappears in another shape in the shadowy region of mystery which surrounds biological and all other questions."
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The foundations of population genetics were laid chiefly by mathematical deduction from basic premises contained in the works of Mendel and Morgan and their followers. Haldane, Wright, and Fisher are the pioneers of population genetics whose main research equipment was paper and ink rather than microscopes, experimental fields, Drosophila bottles, or mouse cages. Theirs is theoretical biology at its best, and it has provided a guiding light for rigorous quantitative experimentation and observation.
— Theodosius Dobzhansky
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The fundamental biological variant is DNA. That is why Mendel's definition of the gene as the unvarying bearer of hereditary traits, its chemical identification by Avery (confirmed by Hershey), and the elucidation by Watson and Crick of the structural basis of its replicative invariance, are without any doubt the most important discoveries ever made in biology. To this must be added the theory of natural selection, whose certainty and full significance were established only by those later theories.
— Jacques Monod
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