"Skullcrack City messes with your mind the way William Burroughs or a bellyful of hallucinogens will do. I'm a longtime fan of Johnson. A master of derangement, he's been bringing it for years. This time, though, it's different. He's burst into the clear and is taking seven-league strides across the literary landscape."

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All I wanted and all Neal wanted and all anybody wanted was some kind of penetration into the heart of things where, like in a womb, we could curl up and sleep the ecstatic sleep that Burroughs was experiencing with a good big mainline shot of M. and advertising executives in NY were experiencing with twelve Scotch & Sodas in Stouffers before they made the drunkard's train to Westchester---but without hangovers.

— Jack Kerouac