"When you advance a frontier, you're doing something that no one has done before. Every time that happens, you have to innovate. You have to think in new ways that hadn't been thought before. You have to invent a new piece of hardware, a new concept, a new law of physics, a new material, a new construction material to enable you to accomplish what it is that you chose to reach for by dreaming about tomorrow."

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I view all art as an effort to translate brain concepts into a work. These brain concepts are synthetic ones - the result of many experiences. But a single work of art, or even a series of works, more often than not cannot translate these synthetic concepts adequately. Yves Saint Laurent once said that he suffered greatly when creating. He is not alone in that. Most artists do the same and say as much.

— Semir Zeki