"The work I have done has, already, been adequately rewarded and recognized. Imagination reaches out repeatedly trying to achieve some higher level of understanding, until suddenly I find myself momentarily alone before one new corner of nature's pattern of beauty and true majesty revealed. That was my reward."

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We know the laws of trial and error, of large numbers and probabilities. We know that these laws are part of the mathematical and mechanical fabric of the universe, and that they are also at play in biological processes. But, in the name of the experimental method and out of our poor knowledge, are we really entitled to claim that everything happens by chance, to the exclusion of all other possibilities?

— Albert Claude